STUDY ON THE EF FICACY OF RECOMBINANT HEPATITIS B VACCINE IN IRANIAN INFANTS

نویسندگان

  • A ZAMANI From the Departments of Pediatrics School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran.
  • H SHAJARI From the Departments of Neonatology, School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran.
  • I SEDIGHY From the Departments of Pediatrics School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran.
چکیده مقاله:

In order to determine the efficacy of recombinant hepatitis B vaccine in Iranian infants, we analyzed the efficacy of a recombinant hepatitis B vaccine in 115 infants aged 12-24 months born to HBsAg negative mothers who received three doses of HBV Antibody to hepatitis B surface antigen (anti-HBs) was checked after the third dose of the vaccine, 94.8% of the infants had developed protective antibody levels. The vaccine was well-tolerated and no serious adverse effects were reported. This study is in agreement with a WHO report which recommends that the easiest and most cost-effective strategy for the control and eventual eradication of HBV would be to immunize all newborns with hepatitis B vaccine only [World Health Organization report, 1984].

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عنوان ژورنال

دوره 14  شماره 4

صفحات  347- 349

تاریخ انتشار 2001-02

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